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MMP14 is required for delamination of chick neural crest cells independently of its catalytic activity

Archive ouverte | Andrieu, Cyril | CCSD

International audience. Matrix metalloproteinases have a broad spectrum of substrates ranging from extracellular matrix components and adhesion molecules to chemokines and growth factors. Despite being mostly secret...

Role of MMP14/MT1-MMP during epithelial-mesenchymal transition and cell migration of neural crest in chick embryo. Rôle de MMP14/MT1-MMP au cours de la transition épithélio-mésenchymateuse et de la migration des crêtes neurales dans l'embryon de poulet

Archive ouverte | Andrieu, Cyril | CCSD

Cell migration is an essential event during embryonic development, immunity and wound healing. Furthermore, the activation of migration program in non-physiologic conditions can have side effects. For example, cell migration promo...

Using Xenopus Neural Crest Explants to Study Epithelial-Mesenchymal Transition

Archive ouverte | Gouignard, Nadège | CCSD

International audience. The epithelial-mesenchymal transition (EMT) converts coherent epithelial structures into single cells. EMT is a dynamic cellular process that is not systematically completed (not all EMTs lea...

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