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Isolated prolapse of the posterior mitral valve leaflet: phenotypic refinement, heritability and genetic etiology

Archive ouverte | Rimbert, Antoine | CCSD

International audience. BACKGROUND: Isolated posterior leaflet mitral valve prolapse (PostMVP), a common form of MVP, often referred as fibroelastic deficiency, is considered a degenerative disease. PostMVP patients...

Mutations in DCHS1 cause mitral valve prolapse

Archive ouverte | Durst, Ronen | CCSD

International audience. Mitral valve prolapse (MVP) is a common cardiac valve disease that affects nearly 1 in 40 individuals. It can manifest as mitral regurgitation and is the leading indication for mitral valve s...

Genetic association analyses highlight biological pathways underlying mitral valve prolapse

Archive ouverte | Dina, Christian | CCSD

International audience. Nonsyndromic mitral valve prolapse (MVP) is a common degenerative cardiac valvulopathy of unknown etiology that predisposes to mitral regurgitation, heart failure and sudden death. Previous f...

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