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Archive ouverte | Kotelevets, Larissa | CCSD

International audience. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor that is frequently down-modulated in human cancer. PTEN inhibits the phosphatidylinositol 3-phosphate kina...

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Archive ouverte | Kotelevets, Larissa | CCSD

International audience. The small GTPase Rac1 has been implicated in a variety of dynamic cell biological processes, including cell proliferation, cell survival, cell-cell contacts, epithelial mesenchymal transition...

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Archive ouverte | Kotelevets, Larissa | CCSD

International audience. Colorectal cancer is a wide-reaching health problem due to its incidence and to the high mortality rates. Adjuvant chemotherapies have considerably improved the prognosis and/or the overall s...

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