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Anti-tumor efficacy of hyaluronan-based nanoparticles for the co-delivery of drugs in lung cancer

Archive ouverte | Jeannot, Victor | CCSD

International audience. Combinations of therapeutic agents could synergistically enhance the response of lung cancer cells. Co-delivery systems capable of transporting chemotherapeutics with different physicochemica...

The PI3K/AKT pathway promotes gefitinib resistance in mutant KRAS lung adenocarcinoma by a deacetylase-dependent mechanism

Archive ouverte | Jeannot, Victor | CCSD

International audience. To select the appropriate patients for treatment with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), it is important to gain a better understanding of the intracellu...

Targeting CD44 receptor-positive lung tumors using polysaccharide-based nanocarriers: Influence of nanoparticle size and administration route

Archive ouverte | Jeannot, Victor | CCSD

International audience. New approaches that are more efficient and able to specifically reach lung tumors are needed. We developed new hyaluronan-based nanoparticles targeting CD44 receptors of two different sizes a...

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