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UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses

Archive ouverte | Aguilar, Esther | CCSD

International audience. Colorectal cancer (CRC) is associated with metabolic and redox perturbation. The mitochondrial transporter uncoupling protein 2 (UCP2) controls cell proliferation in vitro through the modulat...

A readout of metabolic efficiency in arylamine N ‐acetyltransferase‐deficient mice reveals minor energy metabolism changes

Archive ouverte | Denis, Raphaël, G. P. | CCSD

International audience. Recent studies have revealed a possible link between the activities of polymorphic arylamine N-acetyltransferases (NATs) and energy metabolism. We used a Nat1/Nat2 double knockout (KO) mouse ...

Increasing mitochondrial muscle fatty acid oxidation induces skeletal muscle remodeling toward an oxidative phenotype

Archive ouverte | Henique, Carole | CCSD

International audience

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