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Archive ouverte | Arlet, Jean-Benoît | CCSD

Β-TM is an inherited hemoglobinopathy caused by a quantitative defect in the synthesis of the β-globin chains of hemoglobin, leading to the accumulation of free α-globin chains that form toxic aggregates. Despite extensive knowled...

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Archive ouverte | Arlet, Jean-Benoît | CCSD

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Archive ouverte | Arlet, Jean-Benoît | CCSD

International audience. During the past 10 years, the knowledge of iron metabolism has been revolutionized by the discovery of the main regulatory hormone of body iron: hepcidin. Meanwhile, new formulations of ...

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