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Archive ouverte | Galdeano, Carles | CCSD

International audience. Symptomatic treatment of myasthenia gravis is based on the use of peripherally-acting acetylcholinesterase (AChE) inhibitors that, in some cases, must be discontinued due to the occurrence of...

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Archive ouverte | Kliachyna, Maria | CCSD

International audience. A series of new uncharged functional acetylcholinesterase (AChE) reactivators including heterodimers of tetrahydroacridine with 3-hydroxy-2-pyridine aldoximes and amidoximes has been synthesi...

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Archive ouverte | Bourne, Yves | CCSD

International audience. The pentameric ACh-binding proteins (AChBP) from water snails are soluble structural and pharmacological surrogates of the extracellular, ligand-binding domain of nicotinic ACh receptors (nAC...

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