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Systemic Administration of G-CSF Accelerates Bone Regeneration and Modulates Mobilization of Progenitor Cells in a Rat Model of Distraction Osteogenesis

Archive ouverte | Roseren, Flavy | CCSD

International audience. Granulocyte colony-stimulating factor (G-CSF) was shown to promote bone regeneration and mobilization of vascular and osteogenic progenitor cells. In this study, we investigated the effects o...

An efficient and reproducible protocol for distraction osteogenesis in a rat model leading to a functional regenerated femur

Archive ouverte | Pithioux, Martine | CCSD

International audience. This protocol describes the use of a newly developed external fixator for distraction osteogenesis in a rat femoral model. Distraction osteogenesis (DO) is a surgical technique leading to bon...

Mechanical Characterization at the Microscale of Mineralized Bone Callus after Bone Lengthening

Archive ouverte | Roseren, Flavy | CCSD

International audience. Distraction osteogenesis (DO) involves several processes to form an organized distracted callus. While bone regeneration during DO has been widely described, no study has yet focused on the e...

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