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Unilateral and bilateral expression of a quantitative trait: asymmetry and symmetry in coronal craniosynostosis

Archive ouverte | Heuzé, Yann | CCSD

International audience. Bilateral symmetry in vertebrates is imperfect and mild asymmetries are found in normal growth and development. However, abnormal development is often characterized by strong asymmetries. Cor...

FGFR3 overactivation in the brain is responsible for memory impairments in Crouzon syndrome mouse model

Archive ouverte | Cornille, Maxence | CCSD

International audience. Crouzon syndrome with acanthosis nigricans (CAN, a rare type of craniosynostosis characterized by premature suture fusion and neurological impairments) has been linked to a gain-of-function m...

FGF/FGFR Signaling Coordinates Skull Development by Modulating Magnitude of Morphological Integration: Evidence from Apert Syndrome Mouse Models

Archive ouverte | Martínez-Abadías, Neus | CCSD

International audience. The fibroblast growth factor and receptor system (FGF/FGFR) mediates cell communication and pattern formation in many tissue types (e.g., osseous, nervous, vascular). In those craniosynostosi...

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