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RNA uridylation and decay in plants

Archive ouverte | de Almeida, Caroline | CCSD

RNA uridylation consists of the untemplated addition of uridines at the 3' extremity of an RNA molecule. RNA uridylation is catalysed by terminal uridylyltransferases (TUTases), which form a subgroup of the terminal nucleotidyltra...

Molecular connection between the TUTase URT1 and decapping activators

Archive ouverte | Scheer, Hélène | CCSD

Uridylation is a widespread modification destabilizing eukaryotic mRNAs. Yet, molecular mechanisms underlying TUTase-mediated mRNA degradation remain mostly unresolved. Here, we report that the Arabidopsis TUTase URT1 participates...

High-Resolution Mapping of 3' Extremities of RNA Exosome Substrates by 3' RACE-Seq.

Archive ouverte | Scheer, Hélène | CCSD

International audience. The main 3'-5' exoribonucleolytic activity of eukaryotic cells is provided by the RNA exosome. The exosome is constituted by a core complex of nine subunits (Exo9), which coordinates the recr...

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