Afficher la couverture 'CD73: a new biomarker in triple-negative breast cancer | Lafont, Virginie' en grand format
/5

0 avis

CD73: a new biomarker in triple-negative breast cancer

Archive ouverte

Lafont, Virginie | Michaud, Henri-Alexandre | Bonnefoy, Nathalie

Edité par CCSD ; AME Group -

International audience. Triple-negative breast cancer (TNBC) constitute 10–20% of all breast cancers and are characterized by the lack of hormone receptors (estrogen and progesterone receptors) and HER2/neu expression (1). TNBC are not eligible to hormonotherapy and Herceptin/trastuzumab targeted therapy and are generally associated with poor clinical outcome (2). Anthracycline/taxane-based neoadjuvant chemotherapy is the primary systemic treatment but resistance to this treatment is common and the identification of new potential therapeutic molecules is required to improve the outcome of TNBC patients.

Consulter en ligne

Suggestions

Du même auteur

Identification of a regulatory Vδ1 gamma delta T cell subpopulation expressing CD73 in human breast cancer

Archive ouverte | Chabab, Ghita | CCSD

International audience. γδ T cells contribute to the immune response against many cancers, notably through their powerful effector functions that lead to the elimination of tumor cells and the recruitment of other i...

PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody

Archive ouverte | They, Laetitia | CCSD

International audience. Tumor antigen-targeting monoclonal antibodies (TA-targeting mAbs) are used as therapeutics in many malignancies and their capacity to mobilize the host immunity puts them at the forefront of ...

Single-cell high-dimensional imaging mass cytometry: one step beyond in oncology

Archive ouverte | Glasson, Yaël | CCSD

International audience. Solid tumors have a dynamic ecosystem in which malignant and non-malignant (endothelial, stromal, and immune) cell types constantly interact. Importantly, the abundance, localization, and fun...

Chargement des enrichissements...