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Phosphorylation of the Cav3.2 T-type calcium channel directly regulates its gating properties

Archive ouverte | Blesneac, Iulia | CCSD

International audience. Phosphorylation is a major mechanism regulating the activity of ion channels that remains poorly understood with respect to T-type calcium channels (Cav3). These channels are low voltage-acti...

A Ca(v)3.2/syntaxin-1A signaling complex controls T-type channel activity and low-threshold exocytosis.

Archive ouverte | Weiss, Norbert | CCSD

International audience. T-type calcium channels represent a key pathway for Ca(2+) entry near the resting membrane potential. Increasing evidence supports a unique role of these channels in fast and low-threshold ex...

Inhibition of Cav3.2 T-type Calcium Channels by Its Intracellular I-II Loop

Archive ouverte | Monteil, Arnaud | CCSD

International audience. Voltage-dependent calcium channels (Cav) of the T-type family (Cav3.1, Cav3.2, and Cav3.3) are activated by low threshold membrane depolarization and contribute greatly to neuronal network ex...

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