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Archive ouverte | Bouchat, Sophie | CCSD

Reactivation of HIV gene expression in latently infected cells together with an efficient cART has been proposed as an adjuvant therapy aimed at eliminating/decreasing the reservoir size. Results from HIV clinical trials using dea...

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Archive ouverte | Darcis, Gilles | CCSD

International audience. The persistence of latently infected cells in patients under combinatory antiretroviral therapy (cART) is a major hurdle to HIV-1 eradication. Strategies to purge these reservoirs are needed ...

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Archive ouverte | Verdikt, Roxane | CCSD

International audience. Background: The multiplicity, heterogeneity, and dynamic nature of human immunodeficiency virus type-1 (HIV-1) latency mechanisms are reflected in the current lack of functional cure for HIV-...

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