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Impact of exercise training on neuroplasticity-related growth factors in adolescents

Archive ouverte | Pareja-Galeano, Hélios | CCSD

Objectives: We aimed to determine the effect of exercise training on plasma levels of brain-derived neurotrophic factor (BDNF), and serum insulin-like growth factor-1 (IGF-1) as well as cAMP response element-binding (CREB) activat...

G6PD protects from oxidative damage and improves healthspan in mice

Archive ouverte | Nobrega-Pereira, Sandrina | CCSD

Reactive oxygen species (ROS) are constantly generated by cells and ROS-derived damage contributes to ageing. Protection against oxidative damage largely relies on the reductive power of NAPDH, whose levels are mostly determined b...

Overexpression of G6PD as a model of robustness

Archive ouverte | Arc-Chagnaud, Coralie | CCSD

Frailty is a major geriatric syndrome that has been associated to oxidative stress. The antioxidant system is largely based on the reducing power of NADPH, whose levels are mainly determined by the enzyme glucose-6-phosphate dehyd...

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