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Major role of the soluble interleukin-6/interleukin-6 receptor complex for the proliferation of interleukin-6-dependent human myeloma cell lines

Archive ouverte | Gaillard, J. P. | CCSD

International audience. Interleukin-6 (IL-6) is a proinflammatory cytokine which possesses a central growth factor activity for certain tumor cells such as plasma cells in multiple myeloma (MM). Upon binding of IL-6...

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Archive ouverte | Gaillard, J. P. | CCSD

International audience. The receptor for interleukin-6 (IL-6) is characterized by a ligand-binding glycoprotein 80 (gp80) transmembrane chain (IL-6R) which associates with a signal-transducer gp130 chain. We previou...

Major role of the soluble IL-6R (sCD126) for the proliferation of an IL-6-dependent myeloma cell line

Archive ouverte | Gaillard, J. P. | CCSD

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