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Structural organization of the polysomes adjacent to mammalian processing bodies (P-bodies).

Archive ouverte | Cougot, Nicolas | CCSD

International audience. A finely tuned balance of translation, storage and decay of mRNAs (mRNAs) is important for the regulation of gene expression. In eukaryotic cells, this takes place in dynamic cytoplasmic RNA-...

The dual organization of P-bodies revealed by immunoelectron microscopy and electron tomography.

Archive ouverte | Cougot, Nicolas | CCSD

International audience. Processing bodies (P-bodies) are cytoplasmic non-membranous domains involved in the regulation of eukaryotic gene expression. Since their discovery, several studies using fluorescence-based s...

Visualizing Compaction of Polysomes in Bacteria.

Archive ouverte | Cougot, Nicolas | CCSD

International audience. During protein synthesis, many translating ribosomes are bound together with an mRNA molecule to form polysomes (or polyribosomes). While the spatial organization of bacterial polysomes has b...

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