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Circulating biomarkers may be unable to detect infection at the early phase of sepsis in ICU patients: the CAPTAIN prospective multicenter cohort study

Archive ouverte | Parlato, Marianna | CCSD

International audience. PurposeSepsis and non-septic systemic inflammatory response syndrome (SIRS) are the same syndromes, differing by their cause, sepsis being secondary to microbial infection. Microbiological te...

Clustering ICU patients with sepsis based on the patterns of their circulating biomarkers: A secondary analysis of the CAPTAIN prospective multicenter cohort study

Archive ouverte | Misset, Benoît | CCSD

International audience. Background Although sepsis is a life-threatening condition, its heterogeneous presentation likely explains the negative results of most trials on adjunctive therapy. This study in patients wi...

Toll-like receptors expression and interferon-γ production by NK cells in human sepsis.

Archive ouverte | Souza-Fonseca-Guimaraes, Fernando | CCSD

International audience. ABSTRACT: INTRODUCTION: During the course of infection, natural killer (NK) cells contribute to innate immunity by producing cytokines, particularly interferon-gamma (IFN-γ). In addition to t...

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