Deciphering cellular states of innate tumor drug responses

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Deciphering cellular states of innate tumor drug responses

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Edité par CCSD ; BioMed Central -

International audience. The molecular mechanisms underlying innate tumor drug resistance, a major obstacle to successful cancer therapy, remain poorly understood. In colorectal cancer (CRC), molecular studies have focused on drug-selected tumor cell lines or individual candidate genes using samples derived from patients already treated with drugs, so that very little data are available prior to drug treatment.

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