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HoxB genes regulate neuronal delamination in the trunk neural tube by controlling the expression of Lzts1

Archive ouverte | Wilmerding, Axelle | CCSD

International audience. Differential Hox gene expression is central for specification of axial neuronal diversity in the spinal cord. Here, we uncover an additional function of Hox proteins in the developing spinal ...

HOXB8 Counteracts MAPK/ERK Oncogenic Signaling in a Chicken Embryo Model of Neoplasia

Archive ouverte | Wilmerding, Axelle | CCSD

International audience. HOX transcription factors are members of an evolutionarily conserved family of proteinsrequired for the establishment of the anteroposterior body axis during bilaterian development.Although t...

Human ZKSCAN3 and Drosophila M1BP are functionally homologous transcription factors in autophagy regulation

Archive ouverte | Barthez, Marine | CCSD

International audience. Autophagy is an essential cellular process that maintains homeostasis by recycling damaged organelles and nutrients during development and cellular stress. ZKSCAN3 is the sole identified mast...

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