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Proteome-wide adaptations of mouse skeletal muscles during a full month in space

Archive ouverte | Tascher, Georg | CCSD

The safety of space flight is challenged by a severe loss of skeletal muscle mass, strength and endurance that may compromise the health and performance of astronauts. The molecular mechanisms underpinning muscle atrophy and de...

Effectiveness of Resistive Vibration Exercise and Whey Protein Supplementation Plus Alkaline Salt on the Skeletal Muscle Proteome Following 21 Days of Bed Rest in Healthy Males

Archive ouverte | Kenny, Helena | CCSD

International audience. Muscle atrophy is a deleterious consequence of physical inactivity and is associated with increased morbidity and mortality. The aim of this study was to decipher the mechanisms involved in d...

Metabolic reprogramming involving glycolysis in the hibernating brown bear skeletal muscle

Archive ouverte | Chazarin, Blandine | CCSD

Background: In mammals, the hibernating state is characterized by biochemical adjustments, which include metabolic rate depression and a shift in the primary fuel oxidized from carbohydrates to lipids. A number of studies of hiber...

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