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The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1BP to regulate gene transcription

Archive ouverte | Zouaz, Amel | CCSD

International audience. In metazoans, the pausing of RNA polymerase II at the promoter (paused Pol II) has emerged as a widespread and conserved mechanism in the regulation of gene transcription. While critical in r...

Hox Proteins in the Regulation of Muscle Development

Archive ouverte | Poliacikova, Gabriela | CCSD

International audience. Hox genes encode evolutionary conserved transcription factors that specify the anterior–posterior axis in all bilaterians. Being well known for their role in patterning ectoderm-derivatives, ...

Hox functional diversity: Novel insights from flexible motif folding and plastic protein interaction

Archive ouverte | Ortiz-Lombardía, Miguel | CCSD

International audience. How the formidable diversity of forms emerges from developmental and evolutionary processes is one of the most fascinating questions in biology. The homeodomain-containing Hox proteins were r...

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