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Mechanisms of tissue factor induction by the uremic toxin indole-3 acetic acid through aryl hydrocarbon receptor/nuclear factor-kappa B signaling pathway in human endothelial cells

Archive ouverte | Addi, Tawfik | CCSD

International audience. Chronic kidney disease (CKD) is associated with high risk of thrombosis. Indole-3 acetic acid (IAA), an indolic uremic toxin, induces the expression of tissue factor (TF) in human umbilical v...

Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway

Archive ouverte | Gondouin, Bertrand | CCSD

International audience. In chronic kidney disease (CKD), uremic solutes accumulate in blood and tissues. These compounds probably contribute to the marked increase in cardiovascular risk during the progression of CK...

Indole-3 acetic acid predicts cardiovascular event and mortality in chronic kidney disease patients: evidence for an endothelial inflammatory and prooxidant effect

Archive ouverte | Sallée, Marion | CCSD

International audience. no abstract

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