Drosophila Protamine-Like Mst35Ba and Mst35Bb Are Required for Proper Sperm Nuclear Morphology But Are Dispensable for Male Fertility

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Tirmarche, Samantha | Kimura, S. | Sapey-Triomphe, L. | Sullivan, W. | Landmann, F. | Loppin, B.

Edité par CCSD ; Genetics Society of America -

International audience. During spermiogenesis, histones are massively replaced with protamines. A previous report showed that Drosophila males homozygous for a genomic deletion covering several genes including the protamine-like genes Mst35Ba/b are surprisingly fertile. Here, we have precisely deleted the Mst35B locus by homologous recombination, and we confirm the dispensability of Mst35Ba/b for fertility.

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