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Natural killer cell immunotherapies against cancer: checkpoint inhibitors and more

Archive ouverte | Chiossone, Laura | CCSD

International audience. After many years of research, recent advances have shed new light on the role of the immune system in advanced-stage cancer. Various types of immune cells may be useful for therapeutic purpos...

Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor.

Archive ouverte | Walzer, Thierry | CCSD

International audience. Consistent with their function in immune surveillance, natural killer (NK) cells are distributed throughout lymphoid and nonlymphoid tissues. However, the mechanisms governing the steady-stat...

Liver type 1 innate lymphoid cells develop locally via an interferon-γ–dependent loop

Archive ouverte | Bai, Lu | CCSD

International audience. The pathways that lead to the development of tissue-resident lymphocytes, including liver type 1 innate lymphoid cells (ILC1s), remain unclear. We show here that the adult mouse liver contain...

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