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[Basal cell carcinoma with matrical differentiation].. Carcinome basocellulaire à différenciation matricielle

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Goldman-Levy, Gabrielle | Frouin, Eric | Soubeyran, Isabelle | Maury, Géraldine | Guillot, Bernard | Costes, Valérie

Edité par CCSD ; Elsevier Masson -

International audience. Basal cell carcinoma with matrical differentiation is a very rare variant of basal cell carcinoma. To our knowledge, less than 30 cases have been reported. This tumor is composed of basaloid lobules showing a differentiation toward the pilar matrix cells. Recently, it has been demonstrated that beta-catenin would interfer with physiopathogenesis of matrical tumors, in particular pilomatricomas, but also basal cell carcinomas with matrical differentiation. This is a new case, with immunohistochemical and molecular analysis of beta-catenin, in order to explain its histogenesis.

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