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Down-Regulation of GABAA Receptor via Promiscuity with the Vasoactive Peptide Urotensin II Receptor. Potential Involvement in Astrocyte Plasticity

Archive ouverte | Desrues, Laurence | CCSD

International audience. GABA(A) receptor (GABA(A)R) expression level is inversely correlated with the proliferation rate of astrocytes after stroke or during malignancy of astrocytoma, leading to the hypothesis that...

Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity

Archive ouverte | Castel, Hélène | CCSD

International audience

Biochemical and functional characterization of high-affinity urotensin II receptors in rat cortical astrocytes

Archive ouverte | Castel, Hélène | CCSD

International audience. The urotensin II (UII) gene is primarily expressed in the central nervous system, but the functions of UII in the brain remain elusive. Here, we show that cultured rat astrocytes constitutive...

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