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Neurotensin Stimulates Both Calcium Mobilization from Inositol Trisphosphate-Sensitive Intracellular Stores and Calcium Influx through Membrane Channels in Frog Pituitary Melanotrophs

Archive ouverte | Belmeguenai, Amor | CCSD

International audience. Neurotensin (NT) is a potent stimulator of electrical and secretory activities in frog pituitary melanotrophs. The aim of the present study was to characterize the transduction pathways assoc...

Signal Transduction in Rana Melanotrope Cells: Mechanism of Action of Neurotensin on Secretory and Electrical Activities

Archive ouverte | Louiset, Estelle | CCSD

International audience. The pars intermedia of the frog (Rana esculenta) pituitary, which is composed of a single population of endocrine cells, the melanotrophs, is a very suitable model to study the mode of action...

Neurotensin modulates the amplitude and frequency of voltage-activated Ca2+ currents in frog pituitary melanotrophs: implication of the inositol triphosphate/protein kinase C pathway.

Archive ouverte | Belmeguenai, Amor | CCSD

International audience. Many excitatory neurotransmitters and neuropeptides regulate the activity of neuronal and endocrine cells by modulating voltage-operated Ca2+ channels. Paradoxically, however, excitatory neur...

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