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Calreticulin Mutations in Myeloproliferative Neoplasms: Comparison of Three Diagnostic Methods

Archive ouverte | Park, Ji-Hye | CCSD

International audience. Calreticulin (CALR) mutations have recently been reported in 70-84% of JAK2V617F-negative myeloproliferative neoplasms (MPN), and this detection has become necessary to improve the diagnosis ...

Presence of calreticulin mutations in JAK2-negative polycythemia vera

Archive ouverte | Broséus, Julien | CCSD

International audience. Calreticulin (CALR) mutations have been reported in Janus kinase 2 (JAK2)- and myeloproliferative leukemia (MPL)-negative essential thrombocythemia and primary myelofibrosis. In contrast, no ...

Cytokine profiles in Polycythemia Vera and Essential Thrombocythemia patients: clinical implications.

Archive ouverte | Pourcelot, Emmanuel | CCSD

International audience. : Studies have shown that the clinical impact of JAK2 inhibitors in primary myelofibrosis patients is due to the regulation of cytokine levels, suggesting that cytokine profiles might play a ...

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