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Archive ouverte | Vaissière, Anaïs | CCSD

International audience. Background : Small interfering RNAs (siRNAs) are powerful tools to control gene expression. However, due to their poor cellular permeability and stability, their therapeutic development requ...

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Archive ouverte | Deshayes, Sébastien | CCSD

International audience. Gene silencing mediated by double-stranded small interfering RNA (siRNA) has been widely investigated as a potential therapeutic approach for a variety of diseases and, indeed, the first ther...

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Archive ouverte | Konate, Karidia | CCSD

International audience. Abstract Recently, we designed novel amphipathic cell-penetrating peptides, called WRAP, able to transfer efficiently siRNA molecules into cells. In order to gain more information about the r...

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