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Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations

Archive ouverte | Baliakas, Panagiotis | CCSD

International audience. An unresolved issue in chronic lymphocytic leukemia (CLL) is whether IGHV3-21 gene usage, in general, or the expression of stereotyped B-cell receptor immunoglobulin defining subset #2 (IGHV3...

Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors

Archive ouverte | Sutton, Lesley-Ann | CCSD

on behalf of ERIC, the European Research Initiative on CLL. International audience. We report on markedly different frequencies of genetic lesions within subsets of chronic lymphocytic leukemia patients carrying mut...

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL

Archive ouverte | Agathangelidis, Andreas | CCSD

International audience. Chronic lymphocytic leukemia (CLL) is characterized by the existence of subsets of patients with (quasi)identical, stereotyped B-cell receptor (BcR) immunoglobulins. Patients in certain major...

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