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Natural killer cell immunotherapies against cancer: checkpoint inhibitors and more

Archive ouverte | Chiossone, Laura | CCSD

International audience. After many years of research, recent advances have shed new light on the role of the immune system in advanced-stage cancer. Various types of immune cells may be useful for therapeutic purpos...

The 'T-cell-ness' of NK cells: unexpected similarities between NK cells and T cells.

Archive ouverte | Narni-Mancinelli, Emilie | CCSD

International audience. NK cells are considered as prototypical innate immune cells. However, recent discoveries have tended to refine the dogmatic concepts of innate and adaptive immunity. In many ways, NK cells ar...

Type 1 Innate Lymphoid Cells Limit the Antitumoral Immune Response

Archive ouverte | Vienne, Margaux | CCSD

International audience. Natural killer (NK) cells are known to be able to kill established tumor cell lines, but important caveats remain regarding their roles in the detection and elimination of developing primary ...

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