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Pharmacological Profile of Adenosine A2A Receptors in Patients with Lower Extremity Peripheral Artery Disease and Associated Coronary Artery Disease: a Pilot Study

Archive ouverte | Gaudry, Marine | CCSD

International audience. Background: Altered blood flow occurs in patients with low extremity peripheral artery disease (LE-PAD). LE-PAD is mostly associated with coronary artery disease (CAD). Adenosine is an endoge...

Spare Adenosine A2a Receptors Are Associated With Positive Exercise Stress Test In Coronary Artery Disease

Archive ouverte | Ruf, Jean | CCSD

International audience. During exercise, cardiac oxygen-consumption increases and the resulting low oxygen level in myocardium triggers coronary vasodilation. This response to hypoxia is controlled notably by the va...

Homocysteine concentration and adenosine A2A receptor production by peripheral blood mononuclear cells in coronary artery disease patients

Archive ouverte | Deharo, Pierre | CCSD

International audience. Hyperhomocysteinemia is associated with coronary artery disease (CAD). The mechanistic aspects of this relationship are unclear. In CAD patients, homocysteine (HCy) concentration correlates w...

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