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Ligation-dependent RT-PCR: a new specific and low-cost technique to detect ALK, ROS, and RET rearrangements in lung adenocarcinoma

Archive ouverte | Piton, Nicolas | CCSD

International audience. Detection of anaplastic lymphoma kinase (ALK), ROS proto-oncogene 1 (ROS1), and rearranged during transfection (RET) gene rearrangements in lung adenocarcinoma is usually performed by immunoh...

An improved assay for detection of theranostic gene translocations and MET exon 14 skipping in thoracic oncology

Archive ouverte | Piton, Nicolas | CCSD

International audience. Theranostic translocations may be difficult to detect by routine techniques, especially when specimens are exiguous. We recently demonstrated in a series of translocated lung adenocarcinomas ...

Molecular analysis of peripheral non-squamous non-small cell lung cancer sampled by radial EBUS

Archive ouverte | Guisier, Florian | CCSD

International audience. Treatment optimization of non-squamous non-small-cell lung cancers (nonSq-NSCLC) relies on the molecular analysis of the tumour. We aimed to assess the predictive factors of molecular analysi...

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