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Type I High-IFN Gene Signature in Associated with Higher Essdai at Enrollmment and Follow-up in the Prospective Multicenter Assess Cohort of 395 Patients

Archive ouverte | Gottenberg, Jacques-Eric | CCSD

International audience

Serum levels of beta2-microglobulin and free light chains of immunoglobulins are associated with systemic disease activity in primary Sjögren's syndrome. Data at enrollment in the prospective ASSESS cohort.

Archive ouverte | Gottenberg, Jacques-Eric | CCSD

International audience. OBJECTIVES: To analyze the clinical and immunological characteristics at enrollment in a large prospective cohort of patients with primary Sjögren's syndrome (pSS) and to investigate the asso...

Is early-onset primary Sjögren’s syndrome a worse prognosis form of the disease?

Archive ouverte | Anquetil, Céline | CCSD

International audience. Onset of primary SS is usually between 40 and 60 years of age, with severe systemic complications in 15% of cases. We sought to determine whether early-onset disease is related to a specific ...

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