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Detection of glioblastoma response to temozolomide combined with bevacizumab based on µMRI and µPET imaging reveals [$^{18}$F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy

Archive ouverte | Corroyer-Dulmont, Aurélien | CCSD

International audience. The individualized care of glioma patients ought to benefit from imaging biomarkers as precocious predictors of therapeutic efficacy. Contrast enhanced MRI and [18F]-fluorodeoxyglucose (FDG) ...

VEGF-induced BBB permeability is associated with an MMP-9 activity increase in cerebral ischemia: both effects decreased by Ang-1

Archive ouverte | Valable, Samuel | CCSD

International audience. After cerebral ischemia, angiogenesis, by supplying for the deficient perfusion, may be a beneficial process for limiting neuronal death and promoting tissue repair. In this study, we showed ...

Imaging modalities to assess oxygen status in glioblastoma

Archive ouverte | Corroyer-Dulmont, Aurélien | CCSD

CERVOXY. International audience. Hypoxia, the result of an inadequacy between a disorganized and functionally impaired vasculature and the metabolic demand of tumor cells, is a feature of glioblastoma. Hypoxia promo...

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