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Modulateurs peptidiques et peptidomimétiques non compétitifs spécifiques de la glycoprotéine P

Archive ouverte | Arnaud, Ophélie | CCSD

The invention relates to a compound having structure (I), which acts as a non-competitive specific inhibitor of P- glycoprotein (P-gp for "Pleiotropic glycoprotein") and which can be used as a drug, particularly for improving the ...

Advances in peptidomimetics as inhibitors of ABC transporters

Archive ouverte | Ettouati, Laurent | CCSD

International audience

Inhibition of P-glycoprotein-mediated multidrug efflux by aminomethylene and ketomethylene analogs of reversins

Archive ouverte | Koubeissi, Ali | CCSD

International audience. — Several aminomethylene analogs and a ketomethylene analog of reversins were synthesized in order to evaluate their ability to inhibit P-glycoprotein-mediated drug efflux in K562/R7 human le...

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