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mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae , France

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Caspar, Yvan | Maillet, Mylène | Pavese, Patricia | Francony, Gilles | Brion, Jean-Paul | Mallaret, Marie-Reine | Bonnet, Richard | Robin, Frédéric | Beyrouthy, Racha | Maurin, Max

Edité par CCSD ; Centers for Disease Control and Prevention -

International audience. We report intestinal carriage of an extended-spectrum 13-lactamase producing Klebsiella pneumoniae strain with high-level resistance to colistin (MIC 24 mg/L) in a patient in France who had been hospitalized for fungal meningitis. The strain had the mcr-1 plasmid gene and an inactivated mgrB gene, which are associated with colistin resistance.

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