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Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation

Archive ouverte | Hintermair, C. | CCSD

International audience. Eukaryotic RNA polymerase II (Pol II) has evolved an array of heptad repeats with the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7 at the carboxy-terminal domain (CTD) of the large s...

Divergent transcription is associated with promoters of transcriptional regulators

Archive ouverte | Lepoivre, C. | CCSD

International audience. BACKGROUND: Divergent transcription is a wide-spread phenomenon in mammals. For instance, short bidirectional transcripts are a hallmark of active promoters, while longer transcripts can be d...

Novel CD28-Responsive Enhancer Activated by CREB/ATF and AP-1 Families in the Human Interleukin-2 Receptor -Chain Locus

Archive ouverte | Yeh, J.-H. | CCSD

International audience. no abstract

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