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FGF19 is Downregulated in Idiopathic Pulmonary Fibrosis and Inhibits Lung Fibrosis in Mice

Archive ouverte | Justet, Aurélien | CCSD

International audience. IPF is a devastating lung disease with limited therapeutic possibilities. FGF19, an endocrine FGF, was recently shown to decrease liver fibrosis. To ask whether FGF19 had anti-fibrotic proper...

FGF9 prevents pleural fibrosis induced by intra-pleural adenovirus injection in mice

Archive ouverte | Justet, Aurélie | CCSD

International audience. Fibroblast growth factor 9 (FGF9) is necessary for fetal lung development and is expressed by epithelium and mesothelium. We evaluated the role of FGF9 overexpression on adenoviral-induced pl...

Identification of FGFR4 as a regulator of myofibroblast differentiation in Pulmonary Fibrosis

Archive ouverte | Ghanem, Mada | CCSD

International audience. Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with limited therapeutic options. Fibroblast growth factor receptor-4 (FGFR4) is a known receptor for several paracrine fibro...

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