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Functional metagenomics reveals novel pathways of prebiotic breakdown by human gut bacteria

Archive ouverte | Cecchini, Davide | CCSD

The human intestine hosts a complex bacterial community that plays a major role in nutrition and in maintaining human health. A functional metagenomic approach was used to explore the prebiotic breakdown potential of human gut bac...

Highly promiscuous oxidases discovered in the bovine rumen microbiome

Archive ouverte | Ufarté, Lisa | CCSD

The bovine rumen hosts a diverse microbiota, which is highly specialized in the degradation of lignocellulose. Ruminal bacteria, in particular, are well equipped to deconstruct plant cell wall polysaccharides. Nevertheless, their ...

Biochemical identification of the catalytic residues of a glycoside hydrolase family 120 β-xylosidase, involved in xylooligosaccharide metabolisation by gut bacteria

Archive ouverte | Cecchini, Davide | CCSD

In press. The β-xylosidase B from Bifidobacterium adolescentis ATCC15703 belongs to the newly characterized family 120 of glycoside hydrolases. In order to investigate its catalytic mechanism, an extensive kinetic s...

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