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CoverageAnalyzer (CAn): A Tool for Inspection of Modification Signatures in RNA Sequencing Profiles

Archive ouverte | Hauenschild, Ralf | CCSD

International audience

The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent

Archive ouverte | Hauenschild, Ralf | CCSD

International audience. The combination of Reverse Transcription (RT) and high-throughput sequencing has emerged as a powerful combination to detect modified nucleotides in RNA via analysis of either abortive RT-pro...

Illumina-based RiboMethSeq approach for mapping of 2'-O-Me residues in RNA

Archive ouverte | Marchand, Virginie | CCSD

International audience. RNA 2'-O-methylation is one of the ubiquitous nucleotide modifications found in many RNA types from Bacteria, Archaea and Eukarya. RNAs bearing 2'-O-methylations show increased resistance to ...

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