Tropheryma whipplei as a Cause of Epidemic Fever, Senegal, 2010-2012

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Bassene, Hubert | Mediannikov, Oleg | Socolovschi, Cristina | Ă Ratmanov, Pavel | Keita, Alpha K. | Sokhna, Cheikh | Raoult, Didier | Fenollar, Florence

Edité par CCSD ; Centers for Disease Control and Prevention -

International audience. The bacterium Tropheryma whipplei, which causes Whipple disease in ă humans, is commonly detected in the feces of persons in Africa. It is ă also associated with acute infections. We investigated the role of T ă whipplei in febrile patients from 2 rural villages in Senegal. During ă June 2010 March 2012, we collected whole-blood finger-prick samples from ă 786 febrile and 385 healthy villagers. T whipplei was detected in blood ă specimens from 36 (4.6%) of the 786 febrile patients and in 1 (0.25%) ă of the 385 apparently healthy persons. Of the 37 T whipplei cases, 26 ă (70.2%) were detected in August 2010. Familial cases and a potential ă new genotype were observed. The patients' symptoms were mainly headache ă (68.9%) and cough (36.1%). Our findings suggest that T whipplei is a ă cause of epidemic fever in Senegal.

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