Whole-Genome Sequence of a bla(OXA-48)-Harboring Raoultella ornithinolytica Clinical Isolate from Lebanon

Archive ouverte

Al-Bayssari, Charbel | Olaitan, Abiola Olumuyiwa | Leangapichart, Thongpan | Okdah, Liliane | Dabboussi, Fouad | Hamze, Monzer | Rolain, Jean-Marc

Edité par CCSD ; American Society for Microbiology -

International audience. We analyzed the whole-genome sequence of a bla(OXA-48)-harboring Raoultella ornithinolytica clinical isolate from a patient in Lebanon. The size of the Raoultella ornithinolytica CMUL058 genome was 5,622,862 bp, with a G + C content of 55.7%. We deciphered all the molecular mechanisms of antibiotic resistance, and we compared our genome to other available R. ornithinolytica genomes in GenBank. The resistome consisted of 9 antibiotic resistance genes, including a plasmidic bla(OXA-48) gene whose genetic organization is also described.

Consulter en ligne

Suggestions

Du même auteur

First report of colistin-resistant Klebsiella pneumoniae clinical isolates in Lebanon

Archive ouverte | Okdah, Liliane | CCSD

International audience

Deciphering Heteroresistance to Colistin in a Klebsiella pneumoniae Isolate from Marseille, France

Archive ouverte | Bardet, Lucie | CCSD

International audience. Here, we report the description of a colistin-heteroresistant Klebsiella pneumoniae isolate fortuitously isolated from the stool sample of a patient with suspicion of tuberculosis in a public...

New therapy from old drugs: synergistic bactericidal activity of sulfadiazine with colistin against colistin-resistant bacteria, including plasmid-mediated colistin-resistant mcr-1 isolates

Archive ouverte | Okdah, Liliane | CCSD

International audience. The recent emergence of colistin (COL) resistance, particularly mcr-1 plasmid-mediated COL resistance in Gram-negative bacteria, has led to renewed interest in antibiotic combinations to over...

Chargement des enrichissements...