The target cell genus does not matter.

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Bleves, Sophie | Sana, Thibault G | Voulhoux, Romé

Edité par CCSD -

International audience. Two type VI secreted phospholipases D of Pseudomonas aeruginosa were identified as trans-kingdom virulence effectors, targeting both prokaryotic and eukaryotic host cells. Each of them triggers killing bacterial competitors and internalization into non-phagocytic cells. These type VI lipolytic enzymes are widely distributed among pathogens and may constitute a conserved strategy.

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