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Chondrogenic induction of mesenchymal stromal/stem cells from Wharton's jelly embedded in alginate hydrogel and without added growth factor: an alternative stem cell source for cartilage tissue engineering

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Reppel, Loïc | Schiavi, Jessica | Charif, Naceur | Leger, Léonore | Yu, Hao | Pinzano, Astrid | Henrionnet, Christel | Stoltz, Jean-François | Bensoussan, Danièle | Huselstein, Céline

Edité par CCSD ; BioMed Central -

International audience. Due to their intrinsic properties, stem cells are promising tools for new developments in tissue engineering and particularly for cartilage tissue regeneration. Although mesenchymal stromal/stem cells from bone marrow (BM-MSC) have long been the most used stem cell source in cartilage tissue engineering, they have certain limits. Thanks to their properties such as low immunogenicity and particularly chondrogenic differentiation potential, mesenchymal stromal/stem cells from Wharton's jelly (WJ-MSC) promise to be an interesting source of MSC for cartilage tissue engineering.

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