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Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV

Archive ouverte | Rechtien, Anne | CCSD

International audience. Predicting vaccine efficacy remains a challenge. We used a systems vaccinology approach to identify early innate immune correlates of antibody induction in humans receiving the Ebola vaccine ...

Tissue-resident NK cells differ in their expression profile of the nutrient transporters Glut1, CD98 and CD71

Archive ouverte | Salzberger, Wilhelm | CCSD

International audience. Metabolism is a critical basis for immune cell functionality. It was recently shown that NK cell subsets from peripheral blood modulate their expression of nutrient receptors following cytoki...

A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44

Archive ouverte | Niehrs, Annika | CCSD

International audience. Natural killer (NK) cells can recognize virus-infected and stressed cells1 using activating and inhibitory receptors, many of which interact with HLA class I. Although early studies also sugg...

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