Suggestions

Du même auteur

How Zn can impede Cu detoxification by chelating agents in Alzheimer's disease: a proof-of-concept study

Archive ouverte | Conte-Daban, Amandine | CCSD

International audience. The role of Cu and Zn ions in Alzheimer's disease is linked to the consequences of their coordination to the amyloid-β (Aβ) peptide, i.e. to the modulation of Aβ aggregation and to the produc...

Ascorbate Oxidation by Cu(Amyloid-β) Complexes: Determination of the Intrinsic Rate as a Function of Alterations in the Peptide Sequence Revealing Key Residues for Reactive Oxygen Species Production

Archive ouverte | Atrián-Blasco, Elena | CCSD

International audience. Along with aggregation of the amyloid-β (Aβ) peptide and subsequent deposit of amyloid plaques, oxidative stress is an important feature in Alzheimer's disease. Cu bound to Aβ is able to prod...

Cu and Zn coordination to amyloid peptides: From fascinating chemistry to debated pathological relevance

Archive ouverte | Atrián-Blasco, Elena | CCSD

International audience. Several diseases share misfolding of different peptides and proteins as a key feature for their development. This is the case of important neurodegenerative diseases such as Alzheimer’s and P...

Chargement des enrichissements...