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Involvement of different CD4(+) T cell subsets producing granzyme B in the immune response to Leishmania major antigens.

Archive ouverte | Naouar, Ikbel | CCSD

International audience. The nature of effector cells and the potential immunogenicity of Leishmania major excreted/secreted proteins (LmES) were evaluated using peripheral blood mononuclear cells (PBMCs) from healed...

Validation of Recombinant Salivary Protein PpSP32 as a Suitable Marker of Human Exposure to Phlebotomus papatasi, the Vector of Leishmania major in Tunisia

Archive ouverte | Marzouki, Soumaya | CCSD

International audience. Background During a blood meal, female sand flies, vectors of Leishmania parasites, inject saliva into the host skin. Sand fly saliva is composed of a large variety of components that exert d...

Immunity Against Leishmania major Infection: Parasite-Specific Granzyme B Induction as a Correlate of Protection

Archive ouverte | Boussoffara, Thouraya | CCSD

International audience. Zoonotic cutaneous leishmaniasis (ZCL) caused by Leishmania (L.) major infection is characterized by different clinical presentations which depend in part on the host factors. In attempt to i...

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