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Back-exchange of deuterium in neutron crystallography: characterization by IR spectroscopy

Archive ouverte | Yee, Ai Woon | CCSD

International audience. The application of IR spectroscopy to the characterization and quality control of samples used in neutron crystallography is described. While neutron crystallography is a growing field, the l...

A molecular mechanism for transthyretin amyloidogenesis

Archive ouverte | Yee, Ai Woon | CCSD

International audience. Human transthyretin (TTR) is implicated in several fatal forms of amyloidosis. Many mutations of TTR have been identified; most of these are pathogenic, but some offer protective effects. The...

Intrinsic disorder within the erythrocyte binding-like proteins from Plasmodium falciparum.

Archive ouverte | Blanc, Manuel | CCSD

International audience. The ability of the malaria parasite, Plasmodium falciparum, to proliferate within the human host depends on its invasion of erythrocytes. Erythrocyte binding-like (EBL) proteins play crucial ...

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