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Disseminated rhinovirus C8 infection with infectious virus in blood and fatal outcome in a child with repeated episodes of bronchiolitis.

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Lupo, Julien | Schuffenecker, Isabelle | Morel-Baccard, Christine | Bardet, Julie | Payen, Valérie | Kaiser, Laurent | Constant, Samuel | Lobrinus, Johannes Alexander | Lin-Marq, Nathalie | Lina, Bruno | Morand, Patrice | Tapparel, Caroline

Edité par CCSD ; American Society for Microbiology -

International audience. We report a fatal case of acute lower respiratory tract disease with human rhinovirus C (HRV-C) as the unique cause in a 19-month-old girl with a history of repeated episodes of bronchiolitis. HRV-C type 8 nucleic acids were observed in respiratory, stool, and cerebrospinal fluid samples, and infectious virions were isolated from patient serum after inoculation onto reconstituted airway epithelia.

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